Research Technician I-II (Newell Lab)
Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures for the world’s deadliest diseases and make life beyond cancer a reality.
At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.
The Newell Lab is a highly collaborative group within the Vaccine and Infectious Disease Division of the Fred Hutchinson Cancer Research Center. The lab focuses on the application and development of novel approaches for studying antigen-specific T cells in the context of cancer and infectious diseases. In addition to leveraging expertise in the use of highly-multiplexed peptide-MHC tetramer staining in conjunction with mass cytometry to deeply profile antigen-specific T cells, novel single cell sequencing and computational approaches are being used that allow for improved examination of T cell phenotypes, function, antigen specificity, as well as T cell receptor repertoire. Although the lab focuses mostly on studying the roles of T cells in human health and disease, mouse tumor systems are also employed. A major goal of lab is to identify useful biomarkers of clinical outcomes that take advantage of modern experimental and computational approaches with particular focus on human infectious diseases (most recently including studies of adaptive responses in the context of COVID-19) and cancer.
Our lab is seeking an outstanding Research Technician to work on developing and implementing cutting edge analyses to investigate the roles of T cells in various models of cancer and infectious disease.
Responsibilities
- Learn nuances of implementation of mass cytometry and single-cell sequencing for the analysis of relevant cellular samples
- Application of highly multiplexed peptide-MHC multimer analysis using mass cytometry
- Use of single-cell sequencing-based methods for the analysis of cellular immune responses
- Help support other lab members and their projects.
- Carry out own scientific projects, under the supervision of Evan Newell and/or laboratory staff
Qualifications
MINIMUM QUALIFICATIONS:
- Bachelor’s degree in related scientific field
- Superior organization and communication skills.
- Research Technician I
- Independent research experience outside of course laboratory work is required.
- Familiarity with basic immunology and molecular biology is essential.
- Research Technician II (in addition to Research Technician I minimums)
- At least two years of full-time, post-bachelor’s laboratory experience.
- Experience with flow cytometry and FACS sorting
PREFERRED QUALIFICATIONS:
- Experience with flow cytometry and FACS sorting (Research Technician I)
- Experience with mouse experiments and/or husbandry preferred
- Assay validation and optimization experience a plus
- Molecular tissue culture, DNA/RNA isolation, sequencing, and molecular analysis experience a plus
- Experience/familiarity with R and R Studio viewed favorably
Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.
A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.
Our Commitment to Diversity
We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.