Research Scientist - Peptide Chemist

Drug Delivery Platform Development.

SRI International, an over 75-year strong pioneering research institute, has a rich history supporting government and industry. Our innovations have created new industries, billions of dollars in market value and lasting benefits to society. SRI is organized around broad disciplines and capabilities, with research and development divisions and labs to groups who excel at identifying new opportunities, developing products and creating custom solutions. Our organization is driven by impact - delivering unique solutions for the world's important challenges and transforming ideas into reality for clients and partners.

The Biosciences Division at SRI International has an opening for a Senior Scientist in the Center for Macromolecular Bioscience in Harrisonburg, VA. We are seeking an enthusiastic and motivated peptide chemist with interests in drug development and novel delivery platforms. The scientist should be driven to contribute intellectually to a dynamic team environment and have a desire to participate in therapeutic discovery efforts with an emphasis on developing new platform technologies.

 

The SRI Harrisonburg site focuses on the development of novel platform technologies that enable cell-specific intracellular delivery of biological cargos. Based on this technology, we are actively pursuing novel therapeutics in oncology, neuroscience, cardiovascular and metabolic diseases. Opportunities for career advancement and additional job training at SRI are available. Information on current efforts can be found at:

 

https://www.sri.com/case-studies/targeted-antigen-loaded-liposomes-tall/

https://www.sri.com/announcements/sri-introduces-diacyt-cns-drug-delivery-platform-at-2021-jp-morgan-conference/

 

The scientist will be asked to:

Synthesize, purify, and analyze complex peptides

Initiate and direct peptide optimization campaigns

Perform peptide conjugation to different classes of therapeutics, including biologics

Test peptides and peptide conjugates in cell-based assays

Participate in active research programs in drug delivery, including intracellular delivery of biologic therapies

Oversee research associates and direct their research efforts

Collaborate with scientists from other disciplines (e.g., in chemistry, cancer biology, neuroscience and immunology) in cross-divisional teams.

Develop an independently funded research program supported by a combination of grants and contracts from government and commercial sources.

Interact with government and commercial partners, write scientific papers, and present work at scientific conferences.

Build the SRI’s pipeline of therapies and discovery technologies.

 

SRI International is an independent, nonprofit research center that takes the most advanced R&D from the laboratory to the real world. For more than 70 years, we’ve led the discovery and design of ground-breaking products, technologies, and industries – from the computer mouse, Siri and online banking to medical ultrasound, robotic surgery, cancer treatments, and much more.

 

At SRI, we push innovation to new levels, solve the impossible, and invent solutions that create long-lasting value for the world. We take pride in our long history of innovation, and we foster an environment that nurtures and rewards our employees’ passion to make a difference in the future. We’re driven to take the boldest ideas and turn them into reality. SRI employees work in collaborative teams with people who share a commitment to tackling difficult challenges and important needs in society. Our culture is built on respect, curiosity, empowering champions, and a shared drive to excel. At SRI, we’re inventing a better future together.

Requirements:

PhD in chemistry or related field.

Experience with peptide synthesis and conjugation chemistry is required.

Solid Phase Peptide work

Excellent written and oral communication skills necessary; should work well in interdisciplinary team-based groups.

 

Post-offer, pre-laboratory physical examination may be required. Employment at SRI is contingent on successful completion of a background check.

 

Benefits

SRI offers several competitive benefits including -

·      503(b) package with generous matching by SRI

·      Relocation assistance

·      Medical (with a high-deductible option and HSA vesting by SRI), dental and vision benefits

·      Paid maternity and paternity leave

·      Disability insurance

·      Further learning opportunities with tuition assistance

 

SRI has a competitive benefits package, to view details please go to: https://www.sri.com/resources/benefits/.