Reagent Manufacturing Scientist/Lab Technician III (2580)
The Reagent Manufacturing Scientist is responsible for following established protocols to regularly manufacture reagents for use in the production laboratory, as well as for implementing upgrades to improve the quality and efficiency of manufacturing protocols and processes. They will utilize their understanding of molecular biology, next-generation sequencing, and laboratory automation to solve in-process problems, troubleshoot failures, and develop process improvements. They will also create, edit, and review SOPs, train junior staff, and play a key role in process scaling efforts.
What You’ll Do
- Execute high throughput preparations and dispenses of simple and complex reagents (enzyme formulations, primer combinations, large volume solutions) for our clinical lab using a variety of automated dispensing platforms
- Assist in the receiving, handling, and monitoring of quantities and testing quality of raw materials and finished products
- Document manufacturing activities and quality control results
- Identify and help implement process changes to improve the quality and throughput of reagent manufactures. This will include developing measures of material quality, improving preparation efficiency and quality (including automation), and other process improvements
- BS in Molecular Biology or related discipline; Two or more years industry experience in a CGMP industrial molecular biology group, performing reagent manufacturing and quality control testing
- Experience with NGS protocols, a plus
- Hands on experience with laboratory automation/high throughput liquid dispensers
- Familiarity with range of molecular biology techniques (qPCR, DNA extraction, DNA sequencing) and proficiency with molecular biology calculations (dilutions, DNA and protein concentration measurements, enzyme activity measurements); there will be a test!
- Attention to detail and the ability to develop and follow written procedures
- Adaptability to changes in a fast-paced environment
- Some schedule flexibility- occasional overtime hours may be required
- Basic proficiency with computers (Excel, other Office tools) and statistics
Physical & Lifting Requirements
- Lifting Requirements - medium work or exerting up to 50 pounds of force occasionally, 20 pound of force frequently, and 10 pounds of force consistently.
- Physical Requirements - stationary positioning, moving, operating, ascending/descending, communicating, observing, reaching and repetitive motion.
- Use of equipment and tools necessary to perform essential job functions.
- Hazards and Atmospheric Conditions - exposure to fumes, dust, extreme temperatures, wet and/or humid, noise, vibration, mists or gases, mechanical hazards, chemical hazards, electrical hazards and radiant energy hazards. OSHA Category I - duties performed routinely requires exposure to blood, body fluid and tissue.