The Oncology and Immune Unit (OIU) at WuXi AppTec has its focus on providing immunological service of preclinical and clinical studies to facilitate drug discovery in cancer, autoimmune and inflammatory diseases. Our platforms include:
a. in vitro and in vivo CRISPR screens to identify potential targets in large scale;
b. in vitro target validation on tumor or immune cells;
c. immune response evaluation in syngeneic model;
d. multi-panel analysis of tumor infiltrating immune cells by flow cytometry or mass cytometry;
e. humanized mouse model; and
f. clinical biomarker detection.
Our unit has about 800 people, and 70% of them have master or Ph.D. degree. We provide global services and keep long-term cooperation with many clients. Here we can offer immense learning opportunity about professional skill and drug discovery. All passionate scientists with different levels of experience are encouraged to apply.
Responsibilities
The successful candidate will participate in new cancer therapeutic target discovery projects by employing or developing new cutting-edge in vivo cancer models. The candidate is a technical and scientific specialist in the conduct of in vitro cell-based assays, immune cell related assays, and will collaborate with in vivo teams to help the implement of whole projects.
1. Execute cell-based assays including cell culture, lentivirus package and infection, transfection, flow cytometry etc., as well as biochemistry and molecular biology experiments including western blot, DNA/RNA isolation, PCR/RT-qPCR etc.
2. Faithfully record experiment procedures and results
3. Data analysis and report under guidance/supervision of senior scientist
Qualifications
1. M.S. in biochemistry, cell biology or related fields
2. Experience in cell culture is required
3. Experience in biochemistry, molecular biology and cell-based assays is a plus
4. Excellent scientific documentation and reporting proficiency
5. Good communication skills in both English and Mandarin Chinese
