Postdoctoral Fellow - Antibody Engineering, Carter Lab
This Postdoctoral Fellow will be mentored by an experienced researcher with a track record of developing novel technologies that have led to at least ten antibody therapeutics used to treat millions of patients worldwide. The successful candidate will engineer antibodies and other proteins through rational design and molecular evolution technologies to enhance their existing properties or endow them with brand new capabilities. Major lab interests include making intractable targets for antibodies druggable - pursuit of the ‘high-hanging fruit’. Long term research goals for the lab include understanding high concentration properties of antibodies, immunogenicity risk-assessment for engineered antibodies, intracellular delivery of protein therapeutics and applications of AI/ML for antibody optimization.
Requirements:
- A PhD in Molecular Biology, Protein Chemistry, Structural Biology or a related discipline.
- One or more first author research publications in high quality journals in protein/antibody engineering or a related field.
- Experience in protein/antibody engineering from rational design, through generation of mutants, to the expression, purification and characterization of mutant proteins is desirable.
- Expertise with molecular evolution technologies such as yeast or phage display is a plus.
Additional Qualifications:
- Creative individual with a passion for science and capable of independent work in a collaborative environment are particularly encouraged to apply.
- Excellent oral and written communication skills are needed.
Relocation benefits are available for this job posting
More information about the Carter Lab:
More information about the Genentech Postdoctoral Program: