You are viewing a preview of this job. Log in or register to view more details about this job.

Scientist - Protein Analytics

We are the leading provider of therapeutic antibody discovery and engineering technologies. This includes naïve discovery from synthetic libraries in yeast or B cells (mice and humans), antibody engineering and optimization, multi-specific antibody engineering, and a portfolio of proprietary CD3 antibodies licensed non-exclusively for bispecific applications. We focus solely on our partners and not on developing an internal product pipeline. Since 2009, we have partnered with 95 pharmaceutical and biotechnology companies, generating 425 therapeutic programs, over 50 clinical programs, and its first approved product. Our technology has been transferred and implemented at Biogen, GSK, Lilly, Merck, Novo Nordisk, and Takeda. Funded discovery partners include leading pharmaceutical companies, such as Boehringer Ingelheim, Bristol Myers Squibb, Novartis, Regeneron, Sanofi, Takeda and others. Adimab has also partnered with many early-stage venture-backed companies, including Amagma, Cygnal, Dragonfly, iOmx, NextPoint, Pliant, Tizona, TRex Bio and others, as well as mid-size public biopharmaceutical companies such as Acceleron, Alector, Cullinan Oncology, Innovent, Jounce, Mersana, Scholar Rock, Surface Oncology and others.

Our integrated antibody discovery and engineering platform provides unprecedented speed from antigen to purified, full-length human IgGs. We offer fundamental advantages by delivering diverse panels of therapeutically relevant antibodies that meet the most demanding standards for affinity, epitope coverage, species cross-reactivity, and developability. We enable our partners to rapidly expand their biologics pipelines through a broad spectrum of technology access arrangements.

Role
We are seeking a talented scientist with a strong biochemical/biophysical background to join our Protein Analytics team. The successful candidate will work in a small team setting to support Adimab’s novel antibody discovery, maturation, and production platform. This role will closely interface with the Antibody Engineering, Antibody Sciences, High-Throughput Expression, Molecular Core, and Computational Biology teams.

Responsibilities
  • Run biochemical/biophysical assays, including but not limited to, thermal stability (e.g. Tm), UNCLE, CZE, ELISA, analytical SEC and IEX, and RheoSense viscosity measurements.
  • Develop new assays and workflows to support campaign projects.
  • Assist in antigen QC assays, including protein biotinylation, ForteBio Octet kinetics and binning
  • Handle reagent tracking across numerous projects simultaneously
  • Collect, organize, analyze, and interpret antibody characterization data
  • Successfully collaborate with colleagues on the Technical Operations, Antibody Engineering and Antibody Sciences teams

Needed upon hire
  • Requires a Ph.D. in Chemistry, Analytical Chemistry, Biochemistry or a M.S. Degree with 3+ years of industry experience in directly relevant fields
  • Ability to proactively identify and troubleshoot problems, with deep understanding of protein properties
  • Experience with membrane proteins is highly desired 
  • Demonstrated ability to evaluate, interpret, and present scientific data with a mastery of Microsoft Excel and PowerPoint
  • Adaptable and productive in a fast-paced environment
  • Exceptional organization skills and attention to detail
  • Highly motivated with the ability to work independently at the lab bench
  • Adaptable and productive in a fast-paced environment
  • Effective communication skills with the ability to speak openly with colleagues and supervisors
  • Demonstrated success working within a team and collaborating with multiple groups in an organization

Come join us!
As a profitable privately-held biotech company, we take a long-term view on value creation and make substantial investments in technology development, research, and our people. We proudly promote meritocracy and reward employees who are productive, use their resources wisely, and make meaningful contributions to the team. We offer individually tailored compensation packages comprised of a competitive salary, meaningful equity, a 2:1 401(k) match, and comprehensive health care benefits.

Located in New Hampshire’s beautiful Upper Connecticut River Valley, we are minutes from Dartmouth College, the Geisel School of Medicine, the Thayer School of Engineering, the Tuck School of Business, and the Dartmouth Hitchcock Medical Center. We are fortunate to be situated in an area that is renowned for its premier skiing, hiking, and biking.